Actinidin Active®

Kiwifruit Extracts For Health & Well-Being

New Zealand Kiwifruit is a rich, dense source of nutrients, ranking at the top of the most popular fruit varieties in nutritional quality. Kiwienzyme has captured these attributes in its Actinidin Active® kiwifruit extract products to provide a valuable component in the formulation of dietary supplements.

Actinidin Active® kiwifruit extracts are highly concentrated natural products with the functional and nutritional benefits of whole kiwifruit.


  • High in vitamin C and polyphenols, a natural source of anti-oxidants.
  • High in dietary fibre, both soluble and insoluble fibre.
  • Vitamins A, E, B12 and folate + minerals (potassium, calcium, iron and magnesium).
  • The proteolytic enzyme Actinidin.

Supplements incorporating Actinidin® kiwifruit extracts offer real benefits for gut health and relief of oxidative stress.


  • Digestive aid
  • Antioxidant
  • Improved laxation
  • Improved bowel function
  • Prebiotic effect
  • Glycaemic control
  • Cardiovascular benefit

Digestive Aid

Through the proteolytic activity of Actinidin, kiwifruit extracts can enhance upper tract digestion of a variety of food proteins, including meat, soy, casein and cereal proteins (gluten).

Actinidin is not affected by the acid pH of the stomach. As a result of a broad specificity it is able to hydrolyse a wide range of peptide bonds unavailable to pepsin(1).

Following consumption of food, the rate of protein digestion becomes a limiting factor in gastric emptying; dietary supplementation with kiwifruit extracts can enhance the digestion of protein and reduce the negative effects of a high protein diet.

In the elderly population the condition known as Achlorhydria, the absence or reduced production of hydrochloric acid, is quite prevalent. This condition can often result from infections of the gastro-intestinal tract, suppressing acid production. Supplementation with kiwifruit extracts provides the proteolytic activity to help mitigate the long term symptoms of this condition(2).


The production of free radicals during cellular metabolism is considered a primary cause of many of the most serious health issues confronting modern society, including cardiovascular disease, some autoimmune diseases (Arthritis, Multiple Sclerosis) and cancers.

A dietary regime of foods containing natural antioxidants provides the best protection against oxidative stress and resultant health problems. Actinidin® kiwifruit extracts retain the antioxidant properties of whole kiwifruit (ascorbic acid, phenolic acids and flavonoids), confirmed by analysis, providing a valuable source of dietary supplementation.


The composition of gut microflora plays an important role in maintaining bodily health and the prevention of chronic diseases.

New Zealand kiwifruit varieties contain large amounts of soluble and insoluble fibre, including pectic polysaccharides. These slow or non-digestible polysaccharides are the substrates that support the growth of beneficial Lactobaccilus and Bifidobacterium in the gut, fitting the definition of a prebiotic. Promotion of beneficial bacteria mitigates the overgrowth and development of opportunistic bacteria now known to be associated with a wide range of health problems, e.g Heliobacter pylori responsible for gastric ulcers(3).

The prebiotic effect is transient; levels of beneficial bacteria tend to return to baseline levels upon cessation of the fibre intake. Actinidin® kiwifruit extract provides a convenient means of maintaining adequate beneficial dietary fibre.

Improved Bowel Function

Kiwifruit has a demonstrated benefit in improving bowel function and laxation in both the elderly and in patients with Irritable Bowel Syndrome (IBS) and constipation(4).

The insoluble fibre in kiwifruit is indigestible. Due to its high water holding capacity the fibre takes on a volume significantly greater than its dehydrated form, providing the physical bulk to improving faecal consistency.

The reported benefits, taken from population studies, include reduced colon transit time, greater frequency of defaecation and a bulkier and softer stool.

Glycaemic Control

The soluble fibre in kiwifruit is known to absorb water causing it to swell and form a gel. This unique property of the kiwifruit fibre provides important benefits in the gut in controlling absorption of nutrients, in particular the absorption of sugars, into the blood stream.

As a result, kiwifruit has a low Glycaemic Index (GI) providing effective glycaemic control, improved satiety, controlled blood sugars and cholesterol; helping to improve coronary health.

Studies involving athletes performing at high levels of intensity and being hydrated with a kiwifruit fortified energy drink demonstrated longer work times to exhaustion, at higher work loads. Blood volume increased and blood glucose concentrations were maintained without noticeable effect on plasma insulin levels, compared to athletes consuming a placebo(5).

Actinidin® kiwifruit extracts can provide a beneficial ingredient in the formulation of sports hydration products.

Cardiovascular Health

The beneficial effects from fruit and vegetables in vascular health may be explained by a combination of factors including protection of the lipoproteins and vascular walls through their antioxidant and other components. Studies have demonstrated that daily consumption of kiwifruit will reduce platelet aggregation and blood triglycerides, both being implicated in cardiovascular disease(6).


(1) “Influence of Kiwifruit on Protein Digestion” Kaur, L. & Boland, M.
Advances in Food Nutrition Research, Vol 68, Chapt 8 Elsevier Inc 2013 ISSN 1043-4526

(2) “Kiwifruit promotes laxation in the elderly” Rush, E.C., et al
Asia Pacific Journal of Clinical Nutrition, 2002, 11(2), 164-168

(3) “Kiwifruit Changes Intestinal Microbial Profile” Yuan Kun Lee et al.
Microb. Ecol. Health Dis., 2012, 23: 10.3402 / mehd.

(4) “Kiwifruit improves bowel function in patients with irritable bowel syndrome with constipation” Chun-Chao Chang etal.
Asia Pac J. Clin. Nutr. 2010, 19(4), 451-457

(5) “The effects of Kiwi drink supplementation on athletes training in hot environments” Chen J.D. et al.,
Journal of Sports Medicine and Physical Fitness 1990, 30(2), 181-184

(6) “Effects of kiwifruit consumption on platelet aggregation and plasma lipids in healthy human volunteers” Duttaroy A.K. et al.,
Platelets 2004, 15(5), 287-292